circle

We’re putting muscle into finding newtreatments

Our Focus

We are developing potential medicines to improve the healthspan of people with devastating cardiovascular and neuromuscular diseases of impaired muscle function, like heart failure, hypertrophic cardiomyopathies (HCM), amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). By focusing on impacting the mechanics of muscle with investigational medicines that may improve strength, power, or performance, we aspire to develop new treatment options that may dramatically improve the lives and functionality of people living with debilitating diseases.

Image Description

Heart Failure

Heart failure is a progressive condition in which the heart becomes enlarged, thickened or rigid, causing it to become too weak or stiff to fill and pump blood throughout the body.

Image Description

HCM

HCM is a progressive condition that causes the heart to thicken and stiffen, eventually limiting its ability to pump blood.

Image Description

als

In ALS, the progressive death of motor neurons results in diminished stimulation of muscles that perform vital bodily functions, beginning with simple movement and eventually resulting in the loss of respiratory function.

Image Description

sma

SMA is a serious genetic disease characterized by muscle weakness which affects large and fine motor skills, limiting mobility and ultimately breathing.

cardiovascular disease

Image Description

HEART FAILURE

Heart failure is a progressive condition in which the heart becomes enlarged, thickened or rigid, causing it to become too weak or stiff to fill and pump blood throughout the body.

Image Description

Hypertrophic Cardiomyopathy

HCM is a progressive condition that causes the heart to thicken and stiffen, eventually limiting its ability to pump blood.

NEUROMUSCULAR DISEASE

Image Description

als

In ALS, the progressive death of motor neurons results in diminished stimulation of muscles that perform vital bodily functions, beginning with simple movement and eventually resulting in the loss of respiratory function.

Image Description

sma

SMA is a serious genetic disease characterized by severe and progressive muscle weakness which affects large and fine motor skills, limiting mobility and ultimately breathing.