Heart Failure
Heart failure is a progressive condition in which the heart becomes enlarged, thickened or rigid, causing it to become too weak or stiff to fill and pump blood throughout the body.
We’re putting muscle into finding newtreatments
Our Focus
Our Mission
We are developing potential medicines to improve the healthspan of people with devastating cardiovascular and neuromuscular diseases of impaired muscle function, like heart failure, hypertrophic cardiomyopathy (HCM), amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). By focusing on impacting the mechanics of muscle with investigational medicines that may improve strength, power, or performance, we aspire to develop new treatment options that may dramatically improve the lives and functionality of people living with debilitating diseases.
cardiovascular disease
HEART FAILURE
Heart failure is a progressive condition in which the heart becomes enlarged, thickened or rigid, causing it to become too weak or stiff to fill and pump blood throughout the body.
Hypertrophic Cardiomyopathy
HCM is a progressive condition that causes the heart to thicken and stiffen, eventually limiting its ability to pump blood.
NEUROMUSCULAR DISEASE
als
In ALS, the progressive death of motor neurons results in diminished stimulation of muscles that perform vital bodily functions, beginning with simple movement and eventually resulting in the loss of respiratory function.
sma
SMA is a serious genetic disease characterized by severe and progressive muscle weakness which affects large and fine motor skills, limiting mobility and ultimately breathing.