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A PIPELINE POWERED BYPASSION

PUBLICATIONS AND PRESENTATIONS

Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension

PLoS One
Ho D, Chen L, Zhao X, Durham N, Pannirselvam M, Vatner DE, Morgans DJ, Malik FI, Vatner SF, Shen YT
May 2012

Safety, Tolerability and Pharmacodynamics of a Skeletal Muscle Activator in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis
Shefner J, Cedarbaum JM, Cudkowicz ME, Maragakis N, Lee J, Jones D, Watson ML, Mahoney K, Chen M, Saikali K, Mao J
September 2012

The Fast Skeletal Troponin Activator, CK-2017357, Improves Resistance to Fatigue in Healthy, Conscious Rats

Poster, 2012 Experimental Biology Annual Conference
San Diego, CA
Kennedy AR, Heald N, Pakdel A, Ryans J, Russell AJ, Musch T, Poole D, Hageman S, Copp S, Malik FI, Jasper JR
April 2012

The Fast Skeletal Troponin Activator, CK-2017357, Increases Muscle Function and Survival in SOD1 (G93A) Mice; a Model of ALS.

Poster, American Academy of Neurology 2012 Annual Meeting
New Orleans, LA
Malik F, Russell AJ, Pannirselvam M, Hinken AC, Thomsen K, Ardiana A, Godinez G, Jia Z, Saikali KG, Chen MM, Morgans DJ, Jasper JR
April 2012

A Study to Evaluate Safety and Tolerability of CK-2017357 (CK-357) in Patients with Amyotrophic Lateral Sclerosis Using a Twice-Daily, Dose-Titration Regimen

Poster, American Academy of Neurology (AAN) 2012 Annual Meeting
New Orleans, LA
Shefner J, Andrews J, Bedlack R, Berry J, Goslin K, Jackson C, Kissel J, Lange D, Licht J, Mozaffar T, Pestronk A, Rosenfeld J, Wolff A, Lee J, Masonek J, Jones D, Meng L, Cedarbaum J
April 2012