Activating Cardiac Myosin, a Novel Inotropic Mechanism to Improve Cardiac Function in Conscious Dogs with Congestive Heart Failure

Poster, Heart Failure Society of America (HFSA)
Shen YT, Vatner SF, Morgans DJ, Malik F
September 2006

Cardiac Myosin Activator CK-1316719 Increases Myofibril ATPase Activity and Myocyte Contractility in a Rat Model of Heart Failure

Poster, Heart Failure Society of America (HFSA) Annual Meeting
Anderson RL, Kawas RF, Pokrovskii MV, Godinez G, Lee KH, Mak J, Hartman JJ, Morgan BP, Morgans Jr., DJ, Malik F, Sakowicz R, Elias KA
September 2006

A Sensitive Assay for the Basal ATPase Activity of Cardiac Myosin

Poster, Society of Biomolecular Sciences Annual Meeting
Seattle, WA
Baliga R, Rodriguez HM, Guo D, Hartman JJ, Pierce DW, Sakowicz R, Morgan BP, Malik F, Finer JT
September 2006

A Detailed Kinetic Analysis of the Cardiac Myosin Activator, CK-1213296, Suggests It Improves Cardiac Contractility by Accelerating Transition from the Weak to Strongly Bound States

Poster, Molecular Mechanisms of Cardiac Disease and Regeneration
Santa Fe, NM
Rodriguez HM, Sylvester S, Hartman J, Shen YT, Kass DA, Vatner SF, Malik F, Sakowicz R
February 2006

Activation of the Cardiac Sarcomere by a Small Molecule Agent, CK-1213296

Poster, Biophysical Society Annual Meeting
Salt Lake City, UT
Rodriguez HM, Sylvester S, Kawas R, Malik F, Sakowicz R
February 2006