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A PIPELINE POWERED BYPASSION

PUBLICATIONS AND PRESENTATIONS

Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial

The Lancet
Teerlink JR, Felker GM, McMurray JJ, Solomon SD, Adams Jr KF, Cleland JG, Ezekowitz JA, Goudev A, Macdonald P, Metra M, Mitrovic V.
December 2016

Highly Selective Inhibition of Myosin Motors Provides the Basis of Potential Therapeutic Application

Proceedings of the National Academy of Sciences (PNAS)
Sirigu S, Hartman JJ, Planelles-Herrero VJ, Ropars V, Clancy S, Wang X, Chuang G, Qian X, Lu PP, Barrett E, Rudolph K.
November 22, 2016

CK-2127107, a Selective Activator of the Fast Skeletal Muscle Troponin Complex, for the Potential Treatment of Spinal Muscular Atrophy

Poster, 2016 Annual SMA Conference
Orlando, FL
Rudnicki SA, Andrews JA, Malik FI, Wolff AA, Day JW
June 2016

Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): Improved Contractility and Evolution of Ventricular Remodelling Through Time

Poster, Heart Failure 2016
Florence, Italy
Teerlink JR, Felker G, McMurray JV, Solomon SD, Monsalvo ML, Johnston J, Malik FI, Honarpour N
May 2016

Decline in Slow Vital Capacity Predicts Respiratory Insufficiency, Use of Assisted Ventilation, Tracheostomy, or Death

Poster, American Academy of Neurology 2016
Vancouver, BC, Canada
Shefner JM, Meng L, Kulke SF, Rudnicki SA, Wolff AA, Bozik ME, Malik FI, Andrews JA
April 2016