Committed to sharing our science

Committed to sharing our science

338 results available

Effect of Moderate Hepatic Impairment on the Pharmacokinetics of Aficamten and its Metabolites

Poster, American Society for Clinical Pharmacology & Therapeutics (ASCPT) 2024

Xu D, et al

Colorado Springs, CO

March 28, 2024
Drug–Drug Interaction Study to Evaluate the Effect of Strong CYP3A Inhibition and P450 Induction on the Pharmacokinetics of Aficamten and the Effect of Aficamten on P-Glycoprotein in Healthy Participants

Poster, American Society for Clinical Pharmacology & Therapeutics (ASCPT) 2024

Xu D, et al

Colorado Springs, CO

March 28, 2024
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of Aficamten in Healthy Chinese Participants: a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study

Frontiers in Pharmacology

Zhao, X et al

August 22, 2023
COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Shefner, JM et al

May 30, 2023
Relationship between quantitative strength and functional outcomes in the phase 2 FORTITUDE-ALS trial

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Shefner JM, et al

August 29, 2023