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376 results available

Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Omecamtiv Mecarbil

Clinical Pharmacology in Drug Development
Trivedi A, Oberoi RK, Mackowski M, Jafarinasabian P, Zhang H, Flach S, Hutton S, Abbasi S, Dutta S, Lee E
June 9, 2021
Effect of Omecamtiv Mecarbil on the Pharmacokinetics of Metformin, a Probe Substrate for MATE1/MATE2-K, in Healthy Subjects

Clinical Drug Investigation
Trivedi A, Oberoi RK, Jafarinasabian P, Zhang H, Spring M, Flach S, Abbasi S, Dutta S, Lee E
June 7, 2021
Switchability and minimal effect of food on pharmacokinetics of modified release tablet strengths of omecamtiv mecarbil, a cardiac myosin activator

Biopharmaceutics & Drug Disposition
Trivedi A, Oberoi RK, Mackowski M, Jafarinasabian P, Zhang H, Flach S, Simiens M, Terminello B, Abbasi S, Dutta S, Lee E
June 4, 2021
Impact of Ejection Fraction on the Therapeutic Effect of Omecamtiv Mecarbil in Patients with Reduced Ejection Fraction: A Secondary Analysis from GALACTIC-HF

Presentation, American College of Cardiology 70^th Annual Scientific Session & Expo (ACC.21)
Teerlink JR
Virtual
May 17, 2021
Effect of Ejection Fraction on Clinical Outcomes in Patients treated with Omecamtiv Mecarbil in GALACTIC-HF

Journal of the American College of Cardiology
Teerlink JR, Diaz R, Felker GM, McMurray JJ, Metra M, Solomon SD, Biering‐Sørensen T, Böhm M, Bonderman D, et al.
May 16, 2021