Committed to sharing our science

391 results available

The Fast Skeletal Troponin Activator, CK-2017357, Improves Resistance to Fatigue in Healthy, Conscious Rats

Poster, 2012 Experimental Biology Annual Conference
San Diego, CA
Kennedy AR, Heald N, Pakdel A, Ryans J, Russell AJ, Musch T, Poole D, Hageman S, Copp S, Malik FI, Jasper JR
April 2012
The Fast Skeletal Troponin Activator, CK-2017357, Increases Muscle Function and Survival in SOD1 (G93A) Mice; a Model of ALS.

Poster, American Academy of Neurology 2012 Annual Meeting
New Orleans, LA
Malik F, Russell AJ, Pannirselvam M, Hinken AC, Thomsen K, Ardiana A, Godinez G, Jia Z, Saikali KG, Chen MM, Morgans DJ, Jasper JR
April 2012
A Study to Evaluate Safety and Tolerability of CK-2017357 (CK-357) in Patients with Amyotrophic Lateral Sclerosis Using a Twice-Daily, Dose-Titration Regimen

Poster, American Academy of Neurology (AAN) 2012 Annual Meeting
New Orleans, LA
Shefner J, Andrews J, Bedlack R, Berry J, Goslin K, Jackson C, Kissel J, Lange D, Licht J, Mozaffar T, Pestronk A, Rosenfeld J, Wolff A, Lee J, Masonek J, Jones D, Meng L, Cedarbaum J
April 2012
Activation of Fast Skeletal Muscle Troponin as a Potential Therapeutic Approach for Treating Neuromuscular Diseases

Nature Medicine
Russell AJ, Hartman JJ, Hinken AC, Muci AR, Kawas R, Driscoll L, Godinez G, Lee KH, Marquez D, Browne IV WF, Chen MM
March 2012
A Study to Evaluate Safety, Tolerability and Clinical Outcomes Following Repeated Doses of CK-2017357 (CK-357) in Patients with Amyotrophic Lateral Sclerosis

Poster, 22nd International Symposium on ALS/MND
Sydney, Australia
Shefner J, Brooks BR, Simmons Z, Mitsumoto H, Wolff AA, Lee JH, Jones DS, Mao J, Meng L, Cedarbaum JM, The CY 4024 Investigator Group
November 2011