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405 results available

Phase II Safety Study Evaluating the Novel Cardiac Myosin Activator, CK-1827452, in Patients with Ischemic Cardiomyopathy and Angina

Poster, 2009 ESC Heart Failure Congress
Nice, France
Greenberg BH, Chou W, Saikali KG, Escandon R, Lee JH, Chen MM, Malik F, Wolff AA, Shaburishvili T, and the CY 1221 Investigators
June 2009
Echocardiographic Detection of Increases in Ejection Fraction in Patients with Heart Failure Receiving the Selective Cardiac Myosin Activator, CK-1827452

Poster, 2009 ESC Heart Failure Congress
Nice, France
Goldman JH, Teerlink JR, Saikali KG, Malik F and Wolff AA
June 2009
A Direct Inhibitor of Smooth Muscle Myosin as a Novel Therapeutic Approach for the Treatment of Systemic Hypertension.

Poster, American Society of Hypertension 24th Annual Scientific Meeting and Exposition
San Francisco, CA
Qian X, Wang X, Hartman JJ, Jia Z, Clancy S, Yao B, Chuang C, Lu P, Pannirselvam M, Morgans DJ, Morgan BP, Malik FI
May 2009
The Fast Skeletal Troponin Activator, CK-2017357, Increases Skeletal Muscle Force in vitro and in situ

Poster, 2009 Experimental Biology Conference
New Orleans, LA
Russell AJ, Lee K, Jia Z, Muci A, Browne W, Tomlinson M, Hartman JJ, Hansen R, Hinken AC, Albertus D, Claflin D, Morgans DJ., Morgan B, Malik F
April 2009
A Novel Inotropic Agent That Activates Cardiac Myosin and Increases Cardiac Contractility Without Increasing MVO2 in Heart Failure with Left Ventricular Hypertrophy

Poster, 2008 American College of Cardiology Conference (ACC)
Chicago, IL
Shen Y, Zhang Y, Morgans DJ, Vatner SF, Malik F
March 2008