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327 results available

Population Pharmacokinetic-Pharmacodynamic Modeling of Omecamtiv Mecarbil, a cardiac Myosin Activator, in Healthy Volunteers and Patients with Stable Heart Failure

Journal of Clinical Pharmacology
Vu T, Ma P, Xiao JJ, Want YMC, Malik FI, Chow AT
November 2015
The Small Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure

Journal of Pharmacology and Experimental Therapeutics
Hwee DT, Kennedy AR, Hartman JJ, Ryans J, Durham N, Malik FI, Jasper JR
April 2015
Tirasemtiv amplifies skeletal muscle response to nerve activation in humans

Muscle and Nerve
Hansen R, Saikali KG, Chou W, Russell AJ, Chen MM, Vijayakumar V, Stoltz RR, Baudry S, Enoka RM, Morgans DJ, Wolff AA
December 2014
Relationships Between Riluzole and Tirasemtiv Levels on Outcomes in the BENEFIT-ALS Trial

Poster, 25th International Symposium on ALS/MND
Brussels, Belgium
Shefner J, Andrews J, Meng L, Bian Am, Wolff AA, the BENEFIT-ALS Study Group
December 2014
Profile of Medical Care Costs in Patients with Amyotrophic Lateral Sclerosis in the Medicare Program and Under Commercial Insurance

Poster, 25th International Symposium on ALS/MND
Brussels, Belgium
Meng L, Jordan S, Bian A, Andrews J, Shefner J, Wolff A, Blumen H, Iwasaki K, Pyenson B
December 2014