Committed to sharing our science

Committed to sharing our science

391 results available

Pharmacologic Characterization of the Cardiac Myosin Inhibitor, CK-3773274: A Potential Therapeutic Approach for Hypertrophic Cardiomyopathy

Poster, American Heart Association Basic Cardiovascular Sciences (BCVS) 2019 Scientific Sessions
Boston, MA
July 29, 2019
Fast skeletal muscle troponin activator CK‐2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction

Journal of Physiology
Cheng AJ, Hwee DT, Kim LH, Durham N, Yang HT, Hinken AC, Kennedy AR, Terjung RL, JR Jasper, Malik FI, Westerblad H
June 29, 2017
The Fast Skeletal Muscle Troponin Activator, Reldesemtiv, in Combination With SMN-C1 Improves Muscle Function in a Mouse Model of Spinal Muscular Atrophy

Poster, 2019 Cure SMA Annual Meeting
Anaheim, CA
June 2019
The Fast Skeletal Muscle Troponin Activator Reldesemtiv in Combination With Nusinersen Improves Muscle Function in a Mouse Model of Spinal Muscular Atrophy

Poster, 2019 Cure SMA Annual Conference
Anaheim, CA
June 28, 2019
A Phase III Trial of Tirasemtiv as a Potential Treatment for Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Shefner JM, Cudkowicz, ME, Hardiman O, Cockroft BM, Lee JH, Malik FI, Meng L, Rudnicki SA, Wolff, AA, Andrews JA.
May 13, 2019