A Pipeline Powered by Passion

A Pipeline Powered by Passion

scientist testing potential medicines

Pipeline

We're advancing muscle-directed potential treatments for diseases characterized by compromised muscle function, muscle weakness, and fatigue.

Cardiovascular
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Omecamtiv Mecarbil
Cardiac Myosin Activator
HFrEF
Aficamten
Cardiac Myosin Inhibitor
oHCM
Aficamten
Cardiac Myosin Inhibitor
oHCM (Monotherapy vs. SOC)
Aficamten
Cardiac Myosin Inhibitor
Pediatric oHCM
Aficamten
Cardiac Myosin Inhibitor
nHCM
CK-586
Cardiac Myosin Inhibitor
HFpEF
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3

Neuromuscular

Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Approved
Medicines
CK-089
Fast Skeletal Muscle Troponin Activator
Additional skeletal muscle activators
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3

Other

Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Approved
Medicines
Muscle biology-directed research
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Approved

Cardiovascular

Omecamtiv Mecarbil
Cardiac Myosin Activator; HFrEF
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Aficamten
Cardiac Myosin Inhibitor; oHCM
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Aficamten
Cardiac Myosin Inhibitor; oHCM (Monotherapy vs. SOC)
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Aficamten
Cardiac Myosin Inhibitor; Pediatric oHCM
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
Aficamten
Cardiac Myosin Inhibitor; nHCM
Research
Pre-Clinical
Phase 1
Phase 2
Phase 3
CK-586
Cardiac Myosin Inhibitor; HFpEF
Research
Pre-Clinical
Phase 1
Phase 2

Neuromuscular

CK-089
Fast Skeletal Muscle Troponin Activator
Research
Pre-Clinical
Phase 1
Additional skeletal muscle activators
Research
Pre-Clinical

Other

Muscle biology-directed research
Research

All drug candidates are investigational and are not approved by any regulatory agency. Their safety and effectiveness have not been established.