Committed to sharing our science

Committed to sharing our science

335 results available

Cardiac Myosin Inhibitor, CK-586, Minimally Reduces Systolic Function and Ameliorates Obstruction in Feline Hypertrophic Cardiomyopathy

Scientific Reports

Rivas VN, et al.

May 27, 2024
In Vitro and In Vivo Pharmacokinetic Preclinical Characterization of Aficamten, a Small Molecule Cardiac Myosin Inhibitor

Xenobiotica

Sukhun, R et al

August 5, 2024
The Prognostic Value of Peak Oxygen Uptake in Obstructive Hypertrophic Cardiomyopathy: A Literature Review to Inform Economic Model Development

Journal of Medical Economics

Butzner, M et al

July 1, 2024
Pharmacokinetics, Mass Balance, Tissue Distribution, Metabolism, and Excretion of [14C]Aficamten Following Single Oral Dose Administration to Rats

Xenobiotica

Grillo, MP et al

July 26, 2024
Dosing and Safety Profile of Aficamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy: Results From SEQUOIA‐HCM

Journal of the American Heart Association

Coats, CJ et al

July 26, 2024