Committed to sharing our science

Committed to sharing our science

327 results available

Relative Bioavailability of Omecamtiv Mecarbil Pediatric Minitablet Formulations in Healthy Adult Subjects

Clinical Drug Investigation
Trivedi A, Mackowski M, Jafarinasabian P, Zhang H, Flach S, Terminello B, Bhatia A, Dutta S, Lee E
June 10, 2021
Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Omecamtiv Mecarbil

Clinical Pharmacology in Drug Development
Trivedi A, Oberoi RK, Mackowski M, Jafarinasabian P, Zhang H, Flach S, Hutton S, Abbasi S, Dutta S, Lee E
June 9, 2021
Effect of Omecamtiv Mecarbil on the Pharmacokinetics of Metformin, a Probe Substrate for MATE1/MATE2-K, in Healthy Subjects

Clinical Drug Investigation
Trivedi A, Oberoi RK, Jafarinasabian P, Zhang H, Spring M, Flach S, Abbasi S, Dutta S, Lee E
June 7, 2021
Switchability and minimal effect of food on pharmacokinetics of modified release tablet strengths of omecamtiv mecarbil, a cardiac myosin activator

Biopharmaceutics & Drug Disposition
Trivedi A, Oberoi RK, Mackowski M, Jafarinasabian P, Zhang H, Flach S, Simiens M, Terminello B, Abbasi S, Dutta S, Lee E
June 4, 2021
Impact of Ejection Fraction on the Therapeutic Effect of Omecamtiv Mecarbil in Patients with Reduced Ejection Fraction: A Secondary Analysis from GALACTIC-HF

Presentation, American College of Cardiology 70^th Annual Scientific Session & Expo (ACC.21)
Teerlink JR
Virtual
May 17, 2021