Committed to sharing our science

Committed to sharing our science

scientist testing potential medicines

306 results available

A Novel Inotropic Agent That Activates Cardiac Myosin and Increases Cardiac Contractility Without Increasing MVO2 in Heart Failure with Left Ventricular Hypertrophy

Poster, 2008 American College of Cardiology Conference (ACC)
Chicago, IL
Shen Y, Zhang Y, Morgans DJ, Vatner SF, Malik F
March 2008
The Selective Cardiac Myosin Activator, CK-1827452, Increases Systolic Function in a Concentration-Dependent Manner in Patients with Stable Heart Failure

Poster, 2009 Annual American College of Cardiology Conference (ACC)
Orlando, FL
Senior R, Malik FI, Saikali KG, Lee JH, Chen MM, Brand G, Wolff AA, and the CY 1121 Investigators
March 2009
An Automated Apparatus for Isometric Force Analysis of Skinned Muscle Fibers

Poster, Biophysical Society 53rd Annual Meeting
Boston, MA
Marquez D, Tomlinson M, Lievers J, Hartman J, Russell A, Hansen R
March 2009
The Small Molecule Skeletal Sarcomere Activator, CK-1909178, is a Calcium Sensitizer that Binds Selectively to the Fast Skeletal Troponin Complex

Poster, Biophysical Society 53rd Annual Meeting
Boston, MA
Kawas R, Russell A, Rodriguez H, Suekawa K, Muci A, Morgan B, Malik F, Hartman J
March 2009
The Fast Skeletal Troponin Activator, CK-1909178, Increases Skeletal Muscle Force in-vitro and in-situ

Poster, Biophysical Society 53rd Annual Meeting
Boston, MA
Lee K, Hartman J, Hansen R, Clarke D, Hinken A, Muci A, Morgan B, Vijayakumar V, Jia Z, Malik F, Russell A
March 2009