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Fast Skeletal Muscle Troponin Activator Tirasemtiv Increases Muscle Function and Performance in the B6SJL-SOD1G93A ALS Mouse Model

PLoS One
Hwee DT, Kennedy A, Ryans J, Russell AJ, Jia Z, Hinken AC, Morgans DJ, Malik FI, Jasper JR
May 2014
The Fast Skeletal Muscle Troponin Activator Tirasemtiv Increases Muscle Function and Performance in the B6SJL-SOD1G93a ALS Mouse Model.

American Academy of Neurology.
Philadelphia, PA,
April 2014.
Diaphragm Fiber Strength Is Reduced in Critically Ill Patients and Restored by a Troponin Activator

Respiratory and Critical Care Medicine
Hooijman PE, Beishuizen A, De Waard MC, De Man FS, Vermeijden JW, Steenvoorde P, Bouwman RA, Lommen W, Van Hees HW, Heunks LM, Dickhoff C
April 2014
Profile of Medical Care Costs in Patients with Amyotrophic Lateral Sclerosis in the Medicare Program and Under Commercial Insurance

American Academy of Neurology 2014 Annual Meeting
Philadelphia, PA
Meng L, Jordan S, Bian A, Andrews J, Shefner J, Wolff A, Blumen H, Iwasaki K, Pyenson B
April 2014
Tirasemtiv, a Novel Activator of Fast Skeletal Muscle, Increases Isometric Force Evoked by Electrical Stimulation of the Anterior Tibialis Muscle in Healthy Male Subjects

American Academy of Neurology 2014 Annual Meeting
Philadelphia, PA
Hansen R, Saikali KG, Chou W, Russell A, Chen M, Vijayakumar V, Stoltz R, Baudry S, Enoka R, Morgans D, Wolff AA, Malik FI
April 2014