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405 results available

Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices of Treatment for a Year in ALS (VITALITY-ALS): Study Design of a Phase III Clinical Trial of Tirasemtiv in ALS

Poster, 2016 MDA Clinical Conference
Arlington, VA
Andrews JA, Wolff AA, Lee J, Barragan D, Meng L, Bian A, Malik FI, Shefner JM
March 2016
Decline in Slow Vital Capacity Predicts Respiratory Insufficiency, Use of Assisted Ventilation, Tracheostomy or Death

Poster, 6th Annual California ALS Research Summit
La Jolla, CA
Andrews, JA, Meng L, Kulke SF, Rudnicki S, Wolff AA, Bozik ME, Malik FI, Shefner JM
January 2016
Pharmacokinetics and Pharmacodynamics of the Selective Fast Skeletal Muscle Troponin Activator, CK-2127107

Poster, 19th Annual SMA Researcher Meeting
Anaheim, CA
Andrews J, Vijaykumar V, James J, Lee J, Miller T, Bian A, Meng L, Malik FI, Wolff A
June 2015
Population Pharmacokinetic-Pharmacodynamic Modeling of Omecamtiv Mecarbil, a cardiac Myosin Activator, in Healthy Volunteers and Patients with Stable Heart Failure

Journal of Clinical Pharmacology
Vu T, Ma P, Xiao JJ, Want YMC, Malik FI, Chow AT
November 2015
The Small Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure

Journal of Pharmacology and Experimental Therapeutics
Hwee DT, Kennedy AR, Hartman JJ, Ryans J, Durham N, Malik FI, Jasper JR
April 2015